COSINA333MRA

Based on official COSINE (Coresine) datasheet and authorized distributor product pages:

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**Description**
- Low-power, zero-drift, RRIO precision instrumentation amplifier
- Operates with a single supply voltage range of 1.8V to 5.5V
- Features rail-to-rail input and output (RRIO) capability
- Gain can be set from 1 to 1000 with a single external resistor
- Housed in MSOP-8 surface mount package
- **Product Status:** Obsolete / End of Life (EOL)

**Features**
- Low offset voltage: 25μV (max)
- Zero drift: 0.05μV/℃
- Low quiescent current: 70μA
- Low input bias current: 200pA (max)
- Rail-to-rail input and output (RRIO)
- Wide supply voltage range: 1.8V ~ 5.5V
- -3dB bandwidth: 250kHz
- Slew rate: 0.25V/μs
- Output current: 50mA
- High CMRR: 120dB
- High PSRR: 130dB
- Unity-gain stable
- No phase reversal
- Extended temperature range: –40°C to +125°C
- Available in MSOP-8 / SOP-8 packages
- RoHS compliant and Pb-free

**Key Specifications** (Typical @ 25°C)
- Number of Channels: Single (1)
- Supply Voltage (Single): 1.8V ~ 5.5V
- Supply Voltage (Dual): ±0.9V ~ ±2.75V
- Quiescent Current (Iq): 70μA
- Input Offset Voltage (Vos): 5μV (typ.) / 25μV (max)
- Input Offset Voltage Drift (Vos TC): 10nV/℃
- Input Bias Current (Ib): 200pA
- Input Offset Current (Ios): 3pA
- Common Mode Rejection Ratio (CMRR): 120dB
- Power Supply Rejection Ratio (PSRR): 130dB
- Gain Bandwidth Product (GBP): 250kHz
- -3dB Bandwidth: 250kHz
- Slew Rate (SR): 0.25V/μs
- Output Current: 50mA
- Voltage Noise Density (en): 50nV/√Hz @ 1kHz
- Operating Temperature: –40°C to +125°C
- Package / Case: MSOP-8

**Alternative Part Numbers** (Reference only – please verify with manufacturer)
- COSINA333-20MR (Gain selectable: G=20 or G=10)
- COSINA333-50MR (Gain selectable: G=50 or G=30)
- COSINA333MRB (MSOP-8, similar series)
- OPA177, LTC6228, AD8628 (functional equivalents – verify compatibility)

**Applications**
- Medical instruments
- ECG and RTD sensor amplifiers
- Data acquisition systems
- Thermocouple amplifiers
- Bridge amplifiers
- Pressure sensors
- Weighing equipment
- Blood glucose monitors
- Precision measurement and signal conditioning

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> **Note:** All parameters are subject to the official COSINE (Coresine) COSINA333MRA datasheet. Specifications are typical values and may vary with operating conditions. This product is obsolete – not recommended for new designs. Please verify all specifications with the manufacturer's official documentation before use.